Immunotherapy Genetics 101

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Immunotherapy for Cancer - NCI
Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. Learn about the types of immunotherapy and what you can expect during treatment.

Definition of immunotherapy - NCI Dictionary of Cancer Terms
Immunotherapy uses the body’s immune system to fight cancer. This animation explains three types of immunotherapy used to treat cancer: nonspecific immune stimulation, T-cell transfer therapy, and immune checkpoint inhibitors.

Center for Immuno-Oncology | Center for Cancer Research
The CCR’s Center for Immuno-oncology (CIO) explores fundamental questions of cancer immunotherapy through rigorous preclinical studies and translates these findings into clinical trials with the goal of developing novel therapies for a spectrum of cancers.

Immune Checkpoint Inhibitors - NCI - National Cancer Institute
Immune checkpoint inhibitors are a type of immunotherapy that block immune checkpoint proteins from binding with partner proteins. Learn about the cancers treated with checkpoint inhibitors and the side effects they may cause.

Side Effects of Immunotherapy - NCI - National Cancer Institute
Immunotherapy side effects happen when the immune system that has been prompted to act against the cancer also acts against healthy cells and tissues in the body. Learn about the types of side effects that immunotherapy might cause and where to go for more information.

AI Tool May Help Guide Use of Cancer Immunotherapy - NCI
A class of immunotherapy drugs called immune checkpoint inhibitors have proven transformative for people with some types of cancer. In a small number of patients with advanced forms of melanoma, lung cancer, and other tumor types, deposits of cancer scattered throughout their bodies simply melt away.

T-cell Transfer Therapy - Immunotherapy - NCI
T-cell transfer therapy is a type of immunotherapy that makes your own immune cells better able to attack cancer. There are two main types of T-cell transfer therapy: tumor-infiltrating lymphocytes (or TIL) therapy and CAR T-cell therapy.

Cancer Treatment Vaccines - Immunotherapy - NCI
Cancer treatment vaccines are a type of immunotherapy that treats cancer by strengthening the body’s natural defenses against the cancer. Unlike cancer prevention vaccines, cancer treatment vaccines are designed to be used in people who already have cancer—they work against cancer cells, not against something that causes cancer.

Nivolumab - NCI - National Cancer Institute
Nivolumab works by binding to and blocking the protein PD-1 on the surface of some cancer cells, which keeps cancer cells from suppressing the immune system. This allows the immune system to attack the cancer cells. Nivolumab is a type of immunotherapy drug called an immune checkpoint inhibitor.

Immunotherapy - SEER Training
Immunotherapy for bladder cancer is used for muscle invasive tumors, and/or patients with metastatic disease. Document immunotherapy details in NAACCR Item # 2660: Text-BRM.

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Blocking Erythropoietin Signaling in Mice Converts Liver Tumors into Immunotherapy Responders  Genetic Engineering and Biotechnology News
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation  Nature
Antibiotic Use at Immunotherapy Initiation Linked to Poorer Outcomes in Advanced cSCC  Physician's Weekly
Novel cancer immunotherapy approach could complement existing CAR-T treatments  News-Medical
Roswell Park Expert to Share Promising Results on New Immunotherapy Approach in Non-Small Cell Lung Cancer  Roswell Park Comprehensive Cancer Center
Adults Build Allergy Tolerance Through Daily Peanut Doses  Technology Networks
Stopping Adjuvant Immunotherapy Early May Not Worsen Outcomes in Resected Metastatic Melanoma  Dermatology Times
New study finds common virus may improve skin cancer treatment outcomes  University of Oxford
RNA “typos” can highlight leukemia cells for immune attack  Fred Hutchinson Cancer Center
Can peanuts treat peanut allergy in adults?  Times of India
Bringing groundbreaking immunotherapy to the patients of North Carolina  The University of North Carolina at Chapel Hill
An orally administered gene editing nanoparticle boosts chemo-immunotherapy in colorectal cancer  Nature
Older Adults Respond Well to Immunotherapy Despite Age-Related Immune System Differences  Johns Hopkins Medicine
Roswell Park Expert to Share Promising Results on New Immunotherapy Approach in Non-Small Cell Lung Cancer  PRWeb
Here’s How to Prime Tumors to be Defeated by Cancer Immunotherapy  UC San Francisco