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Oncogene - Nature
Publishing basic, clinical and translational research on cellular and molecular biology of cancer including resistance to cancer therapies and development of better approaches...

Oncogenes: What They Are & What They Do - Cleveland Clinic
Oncogenes are important classes, or groups, of genetic mutations that cause cancer. They’re mutated forms of genes that control how cells grow and divide. Research shows specific oncogenes drive and support certain cancers. By targeting oncogenes, medical researchers have developed new ways to treat these cancers. What are oncogenes?

Oncogene - Wikipedia
An oncogene is a gene that has the potential to cause cancer. [1] . In tumor cells, these genes are often mutated, or expressed at high levels. [2] Most normal cells undergo a preprogrammed rapid cell death (apoptosis) if critical functions are altered and then malfunction.

Oncogenes, Tumor Suppressor Genes, and DNA Repair Genes
When a proto-oncogene mutates (changes) or there are too many copies of it, it can become turned on (activated) when it is not supposed to be, at which point it's now called an oncogene. When this happens, the cell can start to grow out of control, which might lead to cancer.

Oncogene - National Human Genome Research Institute
An oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is called a proto-oncogene, and it plays a role in regulating normal cell division. Cancer can arise when a proto-oncogene is mutated, changing it into an oncogene and causing the cell to divide and multiply uncontrollably.

Oncogenes - The Cell - NCBI Bookshelf - National Center for ...
Studies of tumor viruses revealed that specific genes (called oncogenes) are capable of inducing cell transformation, thereby providing the first insights into the molecular basis of cancer.

Journal Information | Oncogene - Nature
Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research.

Oncogene | Cancer, Genetics & Molecular Biology | Britannica
An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been altered or mutated from its original form, the proto-oncogene. Operating as a positive growth regulator, the proto-oncogene is involved in promoting the differentiation and proliferation of normal cells.

Definition of oncogene - NCI Dictionary of Cancer Terms
When a proto-oncogene is changed so that too many copies are made or it becomes more active than normal, it is called an oncogene. Oncogenes may cause normal cells to become cancer cells and grow in the body.

Browse Articles | Oncogene - Nature
Correction: MZF1 mediates oncogene-induced senescence by promoting the transcription of p16 INK4A. Dan Wu; Hua Tan; Peiqing Sun

 

 

 

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TFF3 drives Hippo dependent EGFR-TKI resistance in lung adenocarcinoma  Nature.com

Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer  Nature.com

Proto-Oncogene Activation: The Genetic Shift that Fuels Cancer  News-Medical.Net

A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis | Oncogene  Nature.com

Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells | Oncogene  Nature.com

Insight into mammary gland development and tumor progression in an E2F5 conditional knockout mouse model  Nature.com

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8  Nature.com

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer  Nature.com

Pseudokinase TRIB3 stabilizes SSRP1 via USP10-mediated deubiquitination to promote multiple myeloma progression  Nature.com

Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2  Nature.com

NF-κB-activated oncogene inhibition strategy for cancer gene therapy  Nature.com

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer | Oncogene  Nature.com

The discovery of oncogene-induced senescence  Nature.com

Inhibition and degradation of NRAS with a pan-NRAS monobody - Oncogene  Nature.com

The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis  Nature.com

 

 

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